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Single, never married and working. I am cool, friendly, easy going, and fun loving... Hi... new to this and looking for a sweet man who can make me laugh, let me be independent but can take charge When needed and handle himself like a gentleman,,,, no liars or drama kings please,,, if... Oxidative stress during myocardial reperfusion also reduces the bioavailability of the intracellular signaling molecule, nitric oxide, thereby removing its cardioprotective effects. During myocardial reperfusion, ROS are generated by xanthine oxidase mainly from endothelial cells and the re-energized electron transport chain in the cardiomyocyte mitochondria. The identification of the reperfusion injury salvage kinase RISK pathway 8 and the mitochondrial permeability transition pore PTP 9,10 as new targets for cardioprotection has also intensified research in this area.
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Yet, the translation of these beneficial effects into the clinical setting has been disappointing. Infarcted myocardium is depicted in pink, and the viable, at-risk myocardium is stained red. Oxidative stress is part of the oxygen paradox, 21 in which the reoxygenation of ischemic myocardium generates a degree of myocardial injury that greatly exceeds the injury induced by ischemia alone. No potential conflict of interest relevant to this article was reported. This phenomenon is termed the pH paradox.
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